Aortic valve calcium score: does it correlate with mean transaortic gradient?

Abstract Introduction Aortic valvular calcium score (AVCS) is useful in patients with aortic stenosis for whom echocardiography was not conclusive grading its severity. Transcatheter valve implantation (TAVI) an established procedure of treatment symptomatic severe AS. The burden calcification has been associated some TAVI related complications (as perivalvular leaks), but at the same time it well accepted that degree needed to ensure stable anchoring prosthesis annulus. Purpose To assess if there a correlation between and mean transvalvular gradient 6 months after – higher AVCS correlated lower transaortic TAVI? Methods We performed single-center, retrospective cohort study including who underwent preoperative standardized contrast enhanced MSCT available. Clinical echocardiographic data were collected previously (pre-TAVI) follow up (6M-FUP). Results A total 187 included, 54% female age 79.4±9.0 years old. Most had tricuspid (95.7%); 5 bicuspidy 3 bioprothesis. Concerning type, 73.3% new generation main used CoreValve Evolut Pro (33.7%). Also, 38,5% balloon pre-dilation before TAVI. pre-TAVI maximum gradients 76.5±23.2 mmHg 48.3±15.5 mmHg, respectively; area 0.75±0.16 cm2. 2851±1524 AU (Agaston Units); 81.2% women AVCS>1300 74.4% men >2000 AU. Comparing 6M-FUP TAVI, average differential 61±22 40±15 mmHg. negative weak found (pearson coefficient −0.181, p=0.02) −0.191, p=0.014). Discussion conclusion significant predictor death, stroke leaks On other hand, high better seating native annulus during deployment. Nevertheless, did strongly Funding Acknowledgement Type funding sources: None.